Find in this page information about Computational Approaches in Biology and Data Science employing R, Python, Matlab, including computational approaches…

  • for big data analysis in biological sciences (computational biology)
  • to monitor students’ learning and performance in the classroom
  • to implement machine learning methods

Example of Proteomic Analysis of Ovarian Cancer: This example proteomic data analysis, performed in the Matlab computer language, analyzed SELDI-TOF mass spectrometry from blood samples of two groups: ovarian cancer  vs control group. In this example, Matlab scripts are presented to pre-process the data, generate plots of the groups' spectrograms as well as ranking features using a two-way t-statistic. The data analyzed in this example was obtained from the FDA-NCI Clinical Proteomics Program.


Differential in Gene Expression between Fetal and Adult Brains: In this genomic data science project, the goal was to evaluate differences in gene expression between fetal and adult brains. Transcriptome sequencing data (known as RNA-seq) for this genomic data science project was sequenced on an Illumina platform from human post-mortem brains. The raw sequencing data and meta-data related to each brain sample was retrieved from a public database. The data was aligned, quality control performed on the alignments, and gene count levels of expression quantified. With the aid of exploratory and fitting statistical models,  patterns of gene expression were identified between fetus and adult brains. Findings from this genomic data science project provided insights into genes differentially expressed between fetus and adult brains that helps understand human development, and represents an example of reproducible research in genomic sciences.


Applying Data Science Approaches in Biological Sciences Classrooms: Evidence-based decisions in the classroom are key for us as professor to be able to implement adjustments in students' learning, including in biological sciences courses. In this project, I'll be sharing data science approaches, projects, and peer-review publications, that could benefit making pedagogical adjustments in your classrooms.

Recently-Published Reports


Shinny app to predict users' next word: This projects describes the pitch for a shiny app elaborated to predict next-words followings user's words input.


Other biological and non-biological data sciences

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© Felix E. Rivera-Mariani, PhD 2018 The contents of this website reflect the views of the author and does not represent the views of my institution..